Pastorino, A. C.;Kuschnir, F. C.;Arruda, L. K. P.;Casagrande, R. R. D.;Souza, R. G. L. de;Dias, G. A. C.;Silveira, H. H. N.;Cunha, A. J. L. A.;Jacob, Cristina Miuki Abe;Solé, D.

Autor(a) USP:

Jacob, Cristina Miuki Abe

Ano de publicação:


Unidade USP:

Faculdade de Medicina [FM]


zona urbana; periferia; fatores de risco; asma; rinite; adolescentes


OBJECTIVES: To evaluate the sensitization to aeroallergens determined by skin prick test (SPT) in Brazilian adolescents, and to correlate its positivity with the diagnosis of asthma and/or rhinitis based on the written questionnaire (WQ) of ISAAC phase III study. PATIENTS AND METHODS: A total of 996 adolescents (387 boys) were selected by systematic samples. A standard allergen extracts panel (positive/negative control, D pteronyssinus [Dpt], P americana [Pa], B germanica [Bg], dog, cat, fungal and grass mix) was used and its positivity compared with positive responses to asthma, rhinitis or both. RESULTS: Positive SPT to at least one allergen was observed in 466 adolescents (46.8 %), with sensitisation to Dpt in 79.1 %. Positivity to more than one allergen occurred in 232 students (49.8 %). The frequency of positive SPTs was significantly higher among adolescents with asthma (OR = 2.16), rhinitis (OR = 1.69), and asthma and rhinitis (OR = 2.03). Positive SPT to four or more allergens were higher among asthmatics (OR = 2.6) and among adolescents with asthma and rhinitis (OR = 3). CONCLUSIONS: A high sensitisation rate to aeroallergens was observed, significantly higher among those with asthma, rhinitis or a combination of both, especially in multiple sensitisations.


PASTORINO, A. C.; KUSCHNIR, F. C.; ARRUDA, L. K. P.; et al. Sensitisation to aeroallergens in brazilian adolescents living at the periphery of large subtropical urban centres. Allergologia et immunopathologia, Madrid, v. 36, n. 1, p. 9-16, 2008. DOI: 10.1157/13115665.